Browsing by Author "Alvarez, Alejandra R."

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    • Functionalization of stable fluorescent nanodiamonds towards reliable detection of biomarkers for Alzheimer's ... 
      Morales Zavala, Francisco; Casanova Morales, Nathalie; Gonzalez, Raúl B.; Chandia Cristi, América; Estrada, Lisbell D.; Alvizu, Ignacio; Waselowski, Víctor; Guzmán, Fanny; Guerrero, Simón; Oyarzún Olave, Marisol; Rebolledo, Cristian; Rodríguez, Enrique; Armijo, Julien; Bhuyan, Heman; Favre, Mario; Alvarez, Alejandra R.; Kogan Bocian, Marcelo; Maze, Jerónimo R. (BMC, 2018)
      Background: Stable and non-toxic fluorescent markers are gaining attention in molecular diagnostics as powerful tools for enabling long and reliable biological studies. Such markers should not only have a long half-life ...
    • Oxidative stress activates the c-Abl/p73 proapoptotic pathway in Niemann-Pick type C neurons 
      Klein, Andres; Maldonado, Carola; Vargas, Lina M.; Gonzalez, Marcela; Robledo, Fermín; Perez de Arce, Karen; Muñoz, Francisco J.; Hetz Flores, Claudio; Alvarez, Alejandra R.; Zanlungo, Silvana (2011)
      Niemann-Pick type C (NPC) is a neurodegenerative disease characterized by the intralysosomal accumulation of cholesterol leading to neuronal apoptosis. We have previously reported the activation of the c-Abl/p73 proapoptotic ...